Biology of Aging: A Focus on Cellular Senescence

Course description

In 1961, it was discovered that human cells could not reproduce indefinitely and eventually entered a dormant state called senescence. Senescent cells are viable but have permanently lost the ability to reproduce. They accumulate in aging tissues and are considered a key contributor to aging and, consequently, to the development of age-associated chronic diseases. Recent research advances have led to the development of interventions designed to slow the aging process and to promote healthier aging by specifically targeting senescence. These include therapies, particularly the promising experimental agents known as senolytic drugs. You will learn about these promising agents as well as the importance of specialized dietary practices.